Dosage of diazepam is individualized dependant on the situation becoming handled as well as the client's response towards the medication.

地西泮脂溶性较高，肌肉注射吸收慢而不规则，也不完全，血浓度不稳定，其峰值血药浓度比口服还低，故临床上一般不宜采用肌肉注射的方法给药。

Diazepam may be absorbed into plastics, so liquid preparations are certainly not held in plastic bottles or syringes, and so forth. As such, it can leach to the plastic bags and tubing useful for intravenous infusions.

Dosage need to be individualized for maximum advantageous result. Even though the usual daily dosages specified under will fulfill the requirements of most clients, there'll be some who might call for better doses. In this sort of situations dosage ought to be amplified cautiously to prevent adverse results.

A TPSA price of 32,7 Ų signifies a moderate volume of polarity throughout the compound. TPSA is very valuable in health-related chemistry mainly because it displays the flexibility of a molecule to permeate cells. Molecules with PSA price lesser than 60-70 Ų have a much better capacity to permeate cells.[27] The stability amongst its lipophilic and hydrophilic qualities can impact many facets of the molecule’s conduct, which include its solubility, absorption, distribution, metabolism, and possible interactions inside the Organic technique.

Diazepam is indicated for that administration of nervousness Problems or for your small-expression reduction on the signs or symptoms of anxiousness. Anxiety or tension associated with the anxiety of everyday life commonly does not need procedure having an anxiolytic.

低用量テオフィリン（テオドール、テオロング）はジアゼパムの作用を阻害する。

The states of California and Florida supply diazepam to condemned inmates as a pre-execution sedative as element of their lethal injection program, although the state of California hasn't executed a prisoner considering that 2006.

Due to assorted responses to CNS-acting drugs, initiate therapy with lowest dose and improve as demanded. Not for use in pediatric click here clients below 6 months

Diazepam just isn't advisable to be used through pregnancy; it may well harm a fetus. Diazepam passes into breast milk. Breastfeeding even though using diazepam is not really suggested. Withdrawal indicators may well take place should you instantly cease taking diazepam.

Diazepam ought to be stored from the container it arrived in and it is best saved at place temperature, from heat or dampness (absent out of your toilet, one example is). All prescription drugs really should be retained in a safe spot and out of kids’s arrive at.

Contact a healthcare supplier immediately In case you have any new or worsening suicidal ideas or associated signs and symptoms, Specifically uncommon modifications in temper, behaviors, ideas or inner thoughts.

中島らもの自伝的作品「今夜、すべてのバーで」にはアルコール依存症で入院した主人公が不眠症になり、医者にジアゼパムの注射を要求する場面がある。

The two of such kits deliver prescription drugs employing autoinjectors. They are really supposed for use in "buddy aid" or "self-help" administration of your medication in the field ahead of decontamination and supply of your patient to definitive health-related care.[fifty six]